Guidepost cells

Guidepost cells are cells which assist in the subcellular organization of both neuron axon growth and migration[1]. These cells are typically other, sometimes immature, neurons and glial cells [2].

Contents

Identification

Many types of cells serve as guidepost cells. Guidepost cells are identified by their singular importance in neural guidance of other cells[3]. To qualify as a guidepost cell, neurons hypothesized to be influenced by the guidance the cell are examined during development with the guidance cell in question present and missing (either by destroying the cell or through gene knockout).

See also

References

  1. ^ Palka, J; John Palka, Kathleen E. Whitlock, Marjorie A. Murray (1992-02). "Guidepost cells". Current Opinion in Neurobiology 2 (1): 48–54. doi:10.1016/0959-4388(92)90161-D. PMID 1638135. 
  2. ^ Colón-Ramos DA, Shen K, 2008 Cellular Conductors: Glial Cells as Guideposts during Neural Circuit Development. PLoS Biol 6(4): e112. doi:10.1371/journal.pbio.0060112
  3. ^ Bentley, David; Michael Caudy (1983-07-07). "Pioneer axons lose directed growth after selective killing of guidepost cells". Nature 304 (5921): 62–65. doi:10.1038/304062a0. PMID 6866090. 

External links

CNS
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Other
PNS
General
Neurons/
nerve fibers
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Types
Termination

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